Moebius Syndrome

  • results from the underdevelopment of the VI and VII cranial nerves.
  • The VI cranial nerve controls lateral eye movement, and the VII cranial nerve controls facial expression.
  • rare neurological disorder
  • characterized by weakness or paralysis (palsy) of multiple cranial nerves
  • most often affects the 6th (abducens) and 7th (facial) nerves.
  • The disorder is congenital
  • Other abnormalities include underdevelopment of the pectoral muscles and defects of the limbs.
  • can include bone abnormalities in the hands and feet, weak muscle tone (hypotonia), and hearing loss.
  •  delayed development of motor skills (such as crawling and walking), most eventually acquire these skills.
  • may also be associated with a somewhat increased risk of intellectual disability; however, most affected individuals have normal intelligence.
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