Whipple procedure

A surgical procedure  to treat cancer involving on the head of the pancreas, malignant tumors involving the common bile duct, duodenal papilla, or duodenum near the pancreas.


en bloc removal of the distal segment (antrum) of the stomach; the first and second portions of the duodenum; the head of the pancreas; the common bile duct; and the gallbladder.

The head of the pancreas and the duodenum share the same arterial blood supply (the gastroduodenal artery). These arteries run through the head of the pancreas, so that both organs must be removed if the single blood supply is severed. If only the head of the pancreas were removed it would compromise blood flow to the duodenum, resulting in tissue necrosis.


1898 – procedure was originally described by Alessandro Codivilla, an Italian surgeon.

1909 – The first resection for a periampullary cancer was performed by Walther Kausch, a German surgeon.

1935 – improved version of the surgery performed by Allen Whipple, an American surgeon.

There after called the Whipple procedure.


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