Archive | February 2012

Belladonna & opium suppository

Use:

typically to treat moderate to severe pain from spasms of the urinary tract.

It contains 2 medications, belladonna and opium.

Belladonna helps to decrease the spasms. Opium is a narcotic medication that helps to relieve pain.

A note on belladonna and its uses:

Belladonna produces many effects in the body, including relief from spasms of the gastrointestinal tract (stomach and intestines), the bladder, and the biliary tract. This is helpful in controlling conditions such as colitis, spastic bladder, diverticulitis, infant colic, renal and biliary colic, peptic ulcer, and irritable bowel syndrome.

Belladonna also reduces the secretions of many organs, thereby helping to control conditions such as excessive stomach acid production.

Belladonna is used to treat the rigidity, tremor, excessive salivation, and sweating caused by Parkinson’s disease.

Belladonna also is used to treat motion sickness, nausea, vomiting, abdominal cramping associated with menstruation, and to reduce nighttime urination.

Side effects:

  • Nausea
  • vomiting
  • constipation
  • blurred vision
  • increased eye discomfort in bright light
  • lightheadedness
  • dizziness
  • drowsiness
  • dysuria

Procedure:

lubricate supp

Insert the suppository, pointed end first, with your finger until it passes the muscular sphincter of the rectum, about 1/2 to 1 inch in infants and 1 inch in adults. (If not inserted past this sphincter, the suppository may pop out.)

Intrauterine insemination (IUI)

With infertility rates on the rise in seemingly healthy young couples, intrauterine insemination or IUI is becoming more popular. It could be seen as a step in fertility treatments between hormone therapy and invitro fertilization, IVF.

Intrauterine insemination (IUI) is a form of assisted contraception. it is a procedure in which washed, prepared sperm is introduced into the uterus at the time of ovulation. This procedure is often combined with fertility drugs to increase chances of contraception.

Sperm wash protocol

Sperm wash methods:

Simple Sperm Wash

The simple sperm wash technique is the most basic way of washing and preparing sperm for IUI. Semen is diluted in a test tube, with a special solution of antibiotics and protein supplements. It is then placed in a centrifuge, a machine that spins around at extremely high speeds.

As the sperm mixture is spun, sperm cells fall to the bottom of the test tube, producing a mass of dense, highly active sperm. These sperm can then be removed from the test tube and used in IUI. A simple sperm wash takes about 20 to 40 minutes.

Sperm Swim-Up

Semen is placed in a test tube; in some cases, it is previously washed and centrifuged.
A culture medium is carefully placed on top of the semen. The medium is a hospitable environment for the sperm, and healthy sperm will swim up into it. Slow and immotile sperm are left behind, along with most debris in the semen.

The test tube is let stand an hour or so; in some cases it is placed at an angle, and/or in an incubator where past that time the top layer is collected for use.

Finally, the portion retained for use may be washed and centrifuged again.

Density Gradient Sperm Wash (Percoll)

The density gradient sperm wash is one of the most popular sperm washing methods. This is because it also works to separate dead sperm cells, white blood cells, and other waste products from the sperm.

A test tube is filled with multiple layers of liquids of different densities. Semen is then placed on the top layer of liquid and the test tube is spun in a centrifuge. After it is spun, active, healthy sperm will make their way, to the very bottom layer of the liquid in the test tube, while debris and dead sperm will get caught in the top two layers.

These layers can be siphoned off, in order to remove the active sperm from the test tube. This sperm is then used in the IUI procedure. Density gradient sperm washes take approximately 60 minutes.

This procedure is often called just the “Percoll method”, because Percoll was so often used as the density medium, but other density media are now used.

http://www.fertilitycrete.gr/fertility-treatments/sperm-swim-up-percoll

Ketamine and bladder dysfunction

Findings are show a link between the recreational use of ketamine 3 or more times a week and bladder problems that can linger more than a year after its use.

Symptoms:

Associated bladder dysfunction includes:

  • urinary frequency
  • urinary urgency
  • epigastric pain

The recreational use of ketamine reduces bladder capacity to about 200 mls.

Normal bladder capacity is 400-500ml

The bladder capacity has been shown to recover gradually after a year of abstaining from ketamine abuse.

Prognosis:

In extreme cases of chronic ketamine abuse bladder fibrosis has been shown to set in, reducing bladder capacity to less than 50mls with little recovery when ketamine use stops.

Treatment and Management:

  1. Stopping ketamine use
  2. Bladder reconstructive surgery

The medical post. Canadianhealthcarenetworks.ca

Kleine-Levin Syndrome or KLS (also known as Sleeping Beauty Syndrome)

a neurological disorder characterized by recurring periods of excessive amounts of sleeping and eating.

Manifestations:

  • Hypersomnia, patients may spend 18 hours a day asleep.
  • altered mental state during the episode.
  • difficult to arouse from this sleep
  • irritability
  • aggressive when prevented from sleeping.
  • Cognitive impairment
  • confusion
  • Amnesia for the event
  • Hallucination
  • Delusions or experience a dream-like state
  • changes in eating behavior during episodes, exhibiting megaphagia little discrimination in consumption of excessive amounts of food.

 

Etiology:
unknown
Prognosis:
life-long, acute and chronic episodes