Chromosomal Indicators for Prenatal Diagnosis

  1. One parent carrier of a balanced autosomal translocation
  2. Advanced maternal age
  3. Abnormal Down’s syndrome screening test
  4. Ultrasound findings suggestive of Down’s syndrome or other chromosomal disorder
  5. Previous child with autosomal trisomy or similar abnormality
  6. Parent mosaic for chromosomal abnormality
  7. Chromosomal instability syndromes
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