Infant respiratory distress syndrome (IRDS)

also known as Neonatal respiratory distress syndrome, respiratory distress syndrome of newborn, and previously called hyaline membrane disease.

It is a syndrome in premature infants caused by developmental insufficiency of surfactant production and structural immaturity in the lungs.

It can also result from a genetic problem with the production of surfactant associated proteins. RDS affects about 1% of newborn infants and is the leading cause of death in preterm infants.

Manifestations:

  1. tachypnea
  2. cyanosis
  3. glassy appearance of the alveolar membranes

Pathology:

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