Thrifty Gene Hypothesis and Diabetes

proposed by geneticist James V. Neel

hypothesized genes (thrifty genes) that predispose an individual to developing type II diabetes

Thrifty genes are those that enable our human ancestors to efficiently collect, process and store food as fat during periods of food abundance to aid with survival through times of famine.

Hypothesized that the thrifty gene predispose an individual to obesity (with continual food storage as fat) and the development of type II diabetes in constant times of nutritional abundance.


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